RESEARCH STUDIES & Clinical Trials

Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)

NCT02194738

Baptist MD Anderson is currently accepting patients for this trial

N0577 (CODEL): Phase III Intergroup Study of Radiotherapy with Concomitant and Adjuvant Temozolomide versus Radiotherapy with Adjuvant PCV Chemotherapy in Patients with 1p/19q Co-deleted Anaplastic Glioma or Low Grade Glioma

NCT00887146

Baptist MD Anderson is currently accepting patients for this trial

NeMeRe, a Multi-Institutional Retrospective and Prospective Registry of Neoplastic Meningitis in Adults

Baptist MD Anderson is currently accepting patients for this trial

Prospective Registry of Breast Cancer Patients with Axillary Nodal Metastases Identified During Ultrasound Staging at MD Anderson Cancer Center - PA11-1087

Baptist MD Anderson is currently accepting patients for this trial

MammaPrint, BluePrint, and Full-genome Data Linked with Clinical Data to Evaluate New Gene EXpression Profiles: An Adaptable Registry (FLEX Registry)

NCT03053193

Baptist MD Anderson is currently accepting patients for this trial

Optimizing Preventative Adjuvant Linac-based Radiation: the OPAL Trial A Phase II/III Study of Hypofractionated Partial Breast Irradiation in Women with Early Stage Breast Cancer

NCT03077841

Baptist MD Anderson is currently accepting patients for this trial

Eliminating Breast Cancer Surgery in Exceptional Responders to Neoadjuvant Systemic Therapy

NCT02945579

Baptist MD Anderson is currently accepting patients for this trial

A Phase III, Multicenter, Randomized, Open-Label Study Comparing ATEZOLIZUMAB (Anti-PD-L1 Antibody) in Combination with Adjuvant ANTHRACYCLINE/TAXANE-Based Chemotherapy Versus Chemotherapy Alone in Patients with Operable Triple-Negative Breast Cancer

NCT03498716

Baptist MD Anderson is currently accepting patients for this trial

External Beam Radiation to Eliminate Nominal Metastatic Disease (EXTEND): A Randomized Phase II Basket Trial Assessing the Efficacy of Upfront Local Consolidative Therapy (LCT) for Oligometastatic Disease (2018-0349)

NCT03599765

Baptist MD Anderson is currently accepting patients for this trial

A Randomized, Double-Blind, Phase III Study of Pembrolizumab versus Placebo in Combination with Neoadjuvant Chemotherapy and Adjuvant Endocrine Therapy for the Treatment of High-Risk Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2 ) Breast Cancer (KEYNOTE-756)

NCT03725059

Baptist MD Anderson is currently accepting patients for this trial

Phase III Randomized Trial of DFP-10917 vs. Non-Intensive Reinduction (LoDAC, Azacitidine, Decitabine) or Intensive Reinduction (High and termediate Dose Cytarabine Regimens) for Acute Myelogenous Leukemia Patients in Second or Third Salvage

NCT03926624

Baptist MD Anderson is currently accepting patients for this trial

Pivotal Study of The LUM Imaging System for Assisting Intraoperative Detection of Residual Cancer in The Tumor Bed of Female Patients with Breast Cancer

NCT03686215

Baptist MD Anderson is currently accepting patients for this trial

A Phase 3, Randomized, Double-blind, Multicenter Study of Dostarlimab (TSR-042) plus Carboplatin-Paclitaxel versus Placebo plus Carboplatin-Paclitaxel in Patients with Recurrent or Primary Advanced Endometrial Cancer (RUBY)

NCT03981796

Baptist MD Anderson is currently accepting patients for this trial

Randomized, double-blind, phase 3 study of tucatinib or placebo in combination with ado-trastuzumab emtansine (T-DM1) for subjects with unresectable locally-advanced or metastatic HER2+ breast cancer

NCT03975647

Baptist MD Anderson is currently accepting patients for this trial

A Two-arm, Randomized, Non-comparative, Phase 2 Trial of AGEN2034 (anti PD-1) as a Monotherapy or Combination Therapy with AGEN1884 (anti-CTLA4) or with Placebo in Women with Recurrent Cervical Cancer (Second Line) - RaPiDS

NCT03894215

Baptist MD Anderson is currently accepting patients for this trial

A randomized, open-label, phase II study of canakinumab or pembrolizumab as monotherapy or in combination as neoadjuvant therapy in subjects with resectable non-small cell lung cancer (CANOPY-N)

NCT03968419

Baptist MD Anderson is currently accepting patients for this trial

A phase III, multicenter, randomized, open-label trial to evaluate efficacy and safety of ribociclib with endocrine therapy as an adjuvant treatment in patients with hormone receptor-positive, HER2-negative, early breast cancer (New Adjuvant TriAl with Ribociclib [LEE011]: NATALEE).

NCT03701334

Baptist MD Anderson is currently accepting patients for this trial

FLEX: Liquid Biopsy for Breast Cancer, a Pilot Study

Baptist MD Anderson is currently accepting patients for this trial

Genomics in Oncology: Clinical Outcomes and Determinants

Baptist MD Anderson is currently accepting patients for this trial

A Phase 3 Randomized, Placebo-controlled Trial to Evaluate the Safety and Efficacy of Pembrolizumab (MK-3475) and Lenvatinib (E7080/MK-7902) Versus Pembrolizumab Alone as First-line Intervention in Participants with Advanced Melanoma (LEAP-003)

NCT03820986

Baptist MD Anderson is currently accepting patients for this trial

The Spiration IBV Valve System

Baptist MD Anderson is currently accepting patients for this trial

BESPOKE Study of ctDNA Guided Therapy in Colorectal Cancer

NCT04264702

Baptist MD Anderson is currently accepting patients for this trial

A Phase 4, Single-Arm, Open-Label Clinical Study of Pembrolizumab (MK-3475) to Evaluate The Efficacy and Safety of MK-3475 Plus Carboplatin and Investigator Choice Taxane As First-Line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-B10).

NCT04489888

Baptist MD Anderson is currently accepting patients for this trial

A Phase 2 Open-Label Study Evaluating Tolerability and Efficacy of Navitoclax Alone or in Combination with Ruxolitinib in Subjects with Myelofibrosis

NCT03222609

Baptist MD Anderson is currently accepting patients for this trial

EF-32: Pivotal, Randomized, Open-Label Study of Optune® (Tumor Treating Fields, 200kHz) Concomitant With Radiation Therapy and Temozolomide for the Treatment of Newly Diagnosed Glioblastoma

NCT04471844

Baptist MD Anderson is currently accepting patients for this trial

A Phase 2, Open-label, Single-arm Study Evaluating the Efficacy, Safety and Tolerability of Oncolytic Polio/Rhinovirus Recombinant (PVSRIPO) and the Immune Checkpoint Inhibitor Pembrolizumab in the Treatment of Patients with Recurrent Glioblastoma

NCT04479241

Baptist MD Anderson is currently accepting patients for this trial

A Randomized Phase III Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib versus Observation for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein

NCT02201992

Baptist MD Anderson is currently accepting patients for this trial

A Randomized Phase III Trial of Consolidation with Autologous Hematopoietic Cell Transplantation Followed by Maintenance Rituximab vs. Maintenance Rituximab Alone for Patients with Mantle Cell Lymphoma in Minimal Residual Disease-Negative First Complete Remission

NCT03267433

Baptist MD Anderson is currently accepting patients for this trial

Change in Relative Cerebral Blood Volume as a Biomarker for Early Response to Bevacizumab in Patients with Recurrent Glioblastoma

NCT03115333

Baptist MD Anderson is currently accepting patients for this trial

The National Myelodysplastic Syndromes (MDS) Study

NCT02775383

Baptist MD Anderson is currently accepting patients for this trial

A Randomized Phase II/III Open-Label Study Of Ipilimumab And Nivolumab Versus Temozolomide In Patients With Newly Diagnosed MGMT (Tumor O-6- Methylguanine DNA Methyltransferase) Unmethylated Glioblastoma

NCT04396860

Baptist MD Anderson is currently accepting patients for this trial

Randomized Phase II and Phase III Studies of Individualized Treatment for Nasopharyngeal Carcinoma Based on Biomarker Epstein Barr Virus (EBV) Eoxyribonucleic Acid (DNA)

NCT02135042

Baptist MD Anderson is currently accepting patients for this trial

Randomized Phase II/III Trial of Radiotherapy with Concurrent MEDI4736 (Durvalumab) vs. Radiotherapy with Concurrent Cetuximab in Patients with Locoregionally advanced Head and Neck Cancer with a Contraindication to Cisplatin

NCT03258554

Baptist MD Anderson is currently accepting patients for this trial

Randomized Phase II Trial In Early Relapsing or Refractory Follicular Lymphoma

NCT03269669

Baptist MD Anderson is currently accepting patients for this trial

Phase III Randomized Trial of Standard Systemic Therapy (SST) versus Standard Systemic Therapy Plus Definitive Treatment (Surgery or Radiation) of the Primary Tumor in Metastatic Prostate Cancer

NCT03678025

Baptist MD Anderson is currently accepting patients for this trial