Cancers We Treat Brain & Spine Tumor Diagnosis
DOING THE RESEARCH Learn More About Your Diagnosis
Wherever you are in this journey, we are here to help. We’ll walk you through what you need to know in a supportive and informative way.
At Baptist MD Anderson Cancer Center in Jacksonville, Florida, we believe knowledge is power. At every step, you’ll have access to our team of experts, made up of oncologists, radiologists, surgeons, nurses, and more.
Research is key to what we do. As a patient, you’ll have access to clinical research benefits from MD Anderson Cancer Center. All of our care follows MD Anderson’s standards and procedures.
DEFINING, DIAGNOSING AND TREATING Types of Brain & Spine Tumors
There are a variety of different brain and spine tumors. While symptoms and treatment may be similar in some cases, each type of tumor is unique. Because each tumor is different and complex, we work as a multi-disciplinary team to tailored your treatment. This means, from your oncologist to your surgeon, everyone is working together on your case.
What are gliomas?
Gliomas are a family of primary brain and spine tumors that are born in the brain and spine. They are different than secondary brain tumors. Secondary brain tumors spread or metastasize to the brain from another part of the body. They are usually characterized by invasive growth - the tumor cells form roots into the normal brain around the tumor. Consequently, even when the entire visible tumor is removed by the neurosurgeon, the roots are left behind. As such, other treatments are needed after surgery to manage what remains. Although gliomas can spread in the brain and spine, they usually do not spread into the rest of the body.
Unlike other cancers, gliomas are not staged. Instead they are graded. The grade of the tumor is determined by how abnormal the tumor looks under the microscope when examined by the neuropathologist. Generally speaking, the higher the grade, the more abnormal the tumor appears and the more aggressive the tumor behaves. The grade of the tumor cannot be established by imaging.
Subtypes of gliomas include:
- Grade II Diffuse astrocytoma
- Grade III Anaplastic Astrocytoma
- Grade IV glioblastoma
- Myxopapillary ependymoma
- Grade II ependymoma
- Grade III ependymoma
- Grade II Oligodendroglioma
- Grade III Anaplastic Oligodendroglioma
How are gliomas diagnosed?
Imaging is essential to diagnosing and treating brain tumors. The most common imaging methods include CT scan and MRI. While these tests provide valuable information that helps in establishing your treatment plan, surgery is generally necessary to diagnose the tumor. Other tests frequently performed during treatment include blood work to measure blood counts and other body functions.
How are gliomas treated?
Treatment varies from person to person, but may include… XYZ
Learn more about Baptist MD Anderson’s specific approach to treating cancer and how we uniquely care for you:
METASTATIC BRAIN TUMORS
What are metastatic brain tumors?
Metastasis refers to when a tumor spreads to other parts of the body away from its original site. Cancers frequently metastasize (spread) to brain, occurring in about 10 to 30% of patients. Tumors in the brain can cause a variety of neurological symptoms such as seizures, arm or leg weakness or numbness, difficulty speaking, dizziness or balance problems that result in difficulty walking, changes in vision, or headaches. Tumors can be seen on CT scan or MRI. Usually multiple tumors are present in the brain, although occasionally just one tumor is present. In addition to visible tumors, seeds (small deposits of cancer) that cannot be detected on CT or MRI are present that can give rise to tumors in the future.
What is neoplastic or carcinomatosis meningitis?
Spinal fluid is constantly being made by the brain. It flows through and around the brain and spinal cord. Occasionally, cancers can shed or dissolve tumor cells in the spinal fluid, a condition called neoplastic or carcinomatosis meningitis. This is similar to dissolving sugar in water in that you cannot see the dissolved cells in the fluid.
Neoplastic meningitis is uncommon, affecting approximately 5% of patients with solid tumors (i.e., lung cancer or breast cancer). It is more common in leukemia and lymphoma.
METASTATIC EPIDURAL SPINAL CORD COMPRESSION
What is metastatic epidural spinal cord compression?
Spinal cord compression from epidural metastases, also called epidural spinal cord compression, ESCC or MESCC, occurs after cancer metastasizes to the spine, epidural space or brain. MESCC is the most common and dreaded neurological complications of cancer as a result of brain metastasis because it can have irreversible effects, including paralysis, sensory loss and lack of sphincter control.
What are pituitary tumors?
As the name suggests, pituitary tumors are abnormal growths that begin in the pituitary gland. Your pituitary gland is a pea-sized gland located at the bottom of the brain, just above the nasal passages. Sometimes called the “master gland,” your pituitary gland controls most of the hormones released within your body.
Pituitary tumors are common and may not cause noticeable symptoms. However, these types of tumors can disrupt the balance of hormones in your body and lead to endocrine disease, like Cushing’s syndrome or hyperthyroidism. While these tumors are typically noncancerous (meaning will not spread to other areas), they can cause serious health concerns as they are so close to the brain and may affect surrounding tissue. Pituitary carcinomas (cancers) are very rare.
What are acoustic neuromas?
Acoustic neuromas, or vestibular schwannomas, develop from the overproduction of Schwann cells, which cover the vestibular nerve. The vestibular nerve connects the inner ear to the brain and is associated with balance and hearing. Because of their location, pressure from acoustic neuromas can cause hearing loss, a ringing sound and unsteadiness or dizziness.
While acoustic neuromas are not malignant and tend to grow slowly, if at all, these tumors can still cause severe issues and can be fatal if left untreated.
What are medulloblastomas?
Medulloblastomas are fast-growing, high-grade cancerous tumors. These tumors form in the cerebellum, which is located in the bottom part of the brain and the back of the skull.
While medulloblastomas can occur at any age, they most often occur in children. Medulloblastomas are rare, but are the most common form of pediatric brain tumor. Although medulloblastomas grow quickly and may spread, they generally respond well to treatment.
What is neurofibromatosis?
Neurofibromatosis is a rare genetic disorder that affects the growth and development of nerve cells. Primarily, neurofibromatosis causes tumors to grow on nerve tissue. As a nervous system disorder, these tumors can form on your brain, spinal cord and nerves. Tumors are usually not cancerous, but can become so, meaning they can spread to other areas of the Because neurofibromatosis is genetic, the disease can be inherited by parents or form due to a gene mutation.
Neurofibromatosis is divided into three types:
- Type 1 (NF1): Most typically appears in childhood. NF1 is characterized by multiple light-brown skin spots (in the groin and underarms) and deformed bones.
- Type 2 (NF2): Often manifests during teen or adolescent years. NF2 primarily affects nerves that transmit sound and balance, causing hearing loss, ringing in the ears and unsteadiness.
- Schwannomatosis: Typically diagnosed in adults older than 30. This form of neurofibromatosis is the rarest type and can cause severe pain, numbness, tingling and weakness in the fingers and toes.
PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA
What is primary central nervous system lymphoma?
Primary central nervous system (CNS) lymphoma is a rare form of non-Hodgkin’s lymphoma. This cancer develops in the lymph tissue of the primary central nervous system, which consists of the brain, its surrounding membranes and spinal cord. CNS lymphoma may develop in the brain, spinal cord, leptomeninges membranes or even the eye (called ocular lymphoma).
What is chordoma?
Chordoma is a rare type of bone cancer that occurs anywhere along the spine. About half of the cases of chordomas occur in the base of the spine that forms the pelvis. Another third of chordomas are found in the top of spine, at the base of the skull. While only about one in a million are diagnosed with chordomas, they can happen at any age. Most occur in adults between the ages of 40 and 70.
What is chondrosarcoma?
Chondrosarcoma is a rare bone cancer that, even more rarely, can occur in the base of the skull. This type of bone cancer develops in cartilage cells, the tough but flexible connective tissue that cushions bones and joints. Some types of chondrosarcomas grow slowly while others can grow and spread (metastasize) to other areas of the body rapidly.
What is gangliocytoma?
This central nervous system (CNS) tumor is very rare. Made up of mature neurons, gangliocytomas are most likely to occur in the brain’s temporal lobe, but may also form in the cerebellum, brainstem and spinal cord. Generally, these tumors grow slowly and usually do not spread to other areas.
What is olfactory neuroblastoma?
Olfactory neuroblastoma, also known as esthesioneuroblastoma, is a very rare cancer that begins in the upper portion of the nasal cavity, in or near the cribriform plate. This cribriform plate is a bone that contains tiny holes. Olfactory nerves (the nerves that control smell) pass through the cribriform plate and is why olfactory neuroblastomas generally affect your sense of smell. Olfactory neuroblastoma generally begins as a tumor in the nasal cavity, but can spread into the sinuses, brain, eyes, lymph nodes and other areas of the body.
Common Diagnostic Tests
- CT SCAN
- NEUROLOGIC EXAM
- BLOOD TESTS
OUR LOCATION Brain & Spine Tumor Clinics
Our specialized clinics focus on the complex care needed to treat all aspects of your condition. Within our clinics, we bring together our team of experts to care for you - mind, body and spirit - all under one roof. Our singularly focused clinics include:
- Glioma Clinic
- Pituitary, Meningioma and Skull Base Clinic
- Metastases and Radiosurgery Clinic
The brain and spine tumor clinic is located in the main Baptist MD Anderson Cancer Center on Floor 1.
FOR WHATEVER STEP IS NEXT, Baptist MD Anderson is Here for You
Our team of experts are ready to help you navigate the whirlwind of emotions, options and decisions through every aspect of your care.